Label-free optical biosensors for the detection of various biomolecules
- 주제(키워드) Calcium ion (Ca2+) , GPCR (G-protein coupled receptor) , Optical biosensing techniques , Protein aggregation , THz-TDS (Terahertz time-domain spectroscopy)
- 발행기관 고려대학교 KU-KIST융합대학원
- 지도교수 서민아
- 발행년도 2024
- 학위수여년월 2024. 8
- 학위명 석사
- 학과 및 전공 KU-KIST융합대학원 NBIT융합전공
- 원문페이지 43 p
- 실제URI http://www.dcollection.net/handler/korea/000000288584
- UCI I804:11009-000000288584
- DOI 10.23186/korea.000000288584.11009.0001567
- 본문언어 영어
목차
ABSTRACT i
국문 초록 iii
TABLE OF CONTENTS ⅴ
LIST OF FIGURES ⅵ
CHAPTER 1. INTRODUCTION 1
CHAPTER 2. Ca2+ Influx Using Au/PDMS Platform 2
2.1 Background and Motivation 2
2.1.1 G protein-coupled receptor (GPCR) 2
2.1.2 Ca2+ influx via DRD1 2
2.2 Measurements and Analysis 3
2.3 Methods 12
CHAPTER 3. Protein Aggregates Detection Using THz-TDS 14
3.1 Background and Motivation 14
3.1.1 Recombinant protein production in E. coli 14
3.1.2 Protein aggregation 14
3.1.3 Metamaterial-applied THz-TDS 15
3.2 Measurements and Analysis 15
3.3 Methods 24
CHAPTER 4. CONCLUSION 28
REFERENCES 29
