비소세포폐암의 표적 치료
Targeted Therapy for Non-Small Cell Lung Cancer
- 주제(키워드) Non-small cell lung cancer , Molecular targeted therapy , Biomarkers
- 발행기관 대한내과학회
- 발행년도 2020
- 총서유형 Journal
- DOI http://dx.doi.org/10.3904/kjm.2020.95.2.78
- KCI ID ART002775460
- 본문언어 한국어
초록/요약
Treatment of progressive non-small cell lung cancer (NSCLC) has advanced remarkably, due in part to the development of targeted therapies. Several gene alterations, including EGFR, ALK, ROS1, and BRAF, play important roles in carcinogenesis. Therefore, many targeted agents focusing these gene alterations have been developed and proving their therapeutic efficacies in many clinical trials. Now we should test these gene mutations and should apply treatments individually and properly to ensure the maximal survival benefit of each patient. In this review, we summarize the target genes and respective therapeutic agents in NSCLC.
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