Effect of processing method on platycodin D content in Platycodon grandiflorum roots
Effect of processing method on platycodin D content in Platycodon grandiflorum roots
- 주제(키워드) Platycodon grandiflorum Platycodi Radix Platycodin D HPLC–ELSD Processing method
- 발행기관 대한약학회
- 발행년도 2017
- 총서유형 Journal
- KCI ID ART002263793
- 본문언어 영어
초록/요약
Platycodon grandiflorum root is a traditionalmedicine and food material rich in triterpenoid saponins. Its major constituent, platycodin D (PD), is known to havevarious pharmacological properties, but processing methodsmay influence the PD content. In this study, a fullyvalidated HPLC–ELSD method was developed for thequantification of PD in various states of 73 P. grandiflorumroot samples from East Asia, and it exhibited a markedvariation of the content. Furthermore, the effects of processingprocedures such as peeling and drying temperatureon the PD content were investigated using UPLC–ELSDanalysis, and as a result, a significant influence ofprocessing methods such as peeling and heating of sampleson the content was confirmed. Specifically, unpeeledsamples that were dried at 40 C showed the greatest PDcontent. The obtained results could facilitate the reliablestandardization of P. grandiflorum for precise authenticationand efficacious applications.
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