A Comprehensive Review of the Treatment of Atopic Eczema
A Comprehensive Review of the Treatment of Atopic Eczema
- 주제(키워드) Eczema , atopic dermatitis , atopic eczema , treatment , prevention , epidemiology
- 발행기관 대한천식알레르기학회
- 발행년도 2016
- 총서유형 Journal
- UCI G704-SER000002443.2016.8.3.004
- KCI ID ART002100521
- 본문언어 영어
초록/요약
Atopic eczema (AE) is a chronic, inflammatory skin disorder which usually develops in early childhood. In spite of intensive investigations, the causes of AE remain unclear, but are likely to be multifactorial in nature. Environmental factors or genetic-environmental interactions seem to play a key role in disease progression. Among various measures of AE managment, cutaneous hydration, which improves barrier function and relieve itchiness, may be helpful to reduce the need for topical steroid use and therefore should be used as a basic treatment. Avoiding aggravating factors is also a basic treatment of AE. Standard medical treatment with a pharmacologic approach may be necessary if basic treatment fails to control symptoms satisfactorily. Recently, more attention is given to a proactive therapeutic by regular intermittent application of low potency steroids or topical calcineurin inhibitors to prevent new flares. Furthermore, various targeted biologics are being introduced for AE control and are proposed as promising therapies. This paper provides a summary of the recent literature on the manangement of AE and a treatment guideline.
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