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Chronic Cavitary Pulmonary Histoplasmosis in a Non-HIV and Immunocompromised Patient without Overseas Travel History

Chronic Cavitary Pulmonary Histoplasmosis in a Non-HIV and Immunocompromised Patient without Overseas Travel History

초록/요약

Korea is not known as an endemic area for Histoplasma. However, we experienced a case of histoplasmosis in a person who had never been abroad. A 65-year-old femalewas admitted to the hospital for evaluation of multiple lung nodules. A computedtomography (CT) scan of the chest showed multiple ill-defined consolidationsand cavitations in all lobes of both lungs. The patient underwent a CT-guided lung biopsy, and a histopathology study showed findings compatible with histoplasmosis. Based on biopsy results and clinical findings, the patient was diagnosed with chronic cavitary pulmonary histoplasmosis. The patient recovered completely followingitraconazole treatment. This is the first case report of pulmonary histoplasmosisunconnected with either HIV infection or endemicity in Korea.

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