한국 성인의 벌독으로 인한 아나필락시스: 국내 다기관 후향적 연구 : Hymenoptera venom anaphylaxis in adult Korean: a multicenter retrospective case study
Hymenoptera venom anaphylaxis in adult Korean: a multicenter retrospective case study
- 주제(키워드) Hymenoptera , Bee venoms , Anaphylaxis , Apitherapy
- 발행기관 대한 소아알레르기 호흡기학회
- 발행년도 2014
- 총서유형 Journal
- UCI G704-000706.2014.2.5.015
- KCI ID ART001929753
- 본문언어 한국어
초록/요약
Purpose: We investigated the causes, clinical features, and risk factors of bee venom anaphylaxis in Korea. Methods: The medical records of the diagnosis of anaphylaxis during a 5-year period from the 14 hospitals in Korea have been retrospectively reviewed. Cases of bee venom anaphylaxis were identified among anaphylaxis patients, and subgroup analyses were done. Results: A total of 291 patients were included. The common cause of bee species was vespid (24.6%) in bee venom anaphylaxis, followed by honeybee and vespid (8.8%), apitherapy (7.7%), and honeybee (2.0%), although the causative bee species were commonly unknown (56.9%). The severity of anaphylaxis was mostly mild-moderate (72.9%), and common clinical manifestations included cutaneous (80.6%), cardiovascular (39.2%), respiratory (38.1%), and gastrointestinal (13.1%) symptoms. Portable epinephrine auto-injectors were prescribed to 12.1% of the patients. Subject positive to both vespid and honeybee showed more severe symptoms and higher epinephrine use (P<0.05). The severity was significantly associated with older age, but not with gender, underlying allergic disease, or family history. Apitherapy-induced anaphylaxis showed a higher rate of hospitalization and epinephrine use than bee sting anaphylaxis (P<0.05). Conclusion: Vespid is the most common cause of bee venom anaphylaxis in Korea. It is suggested that positivity to honeybee and vespid may be associated with more severe symptoms.
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