Distribution of Doublecortin Immunoreactivities in Developing Chick Retina
Distribution of Doublecortin Immunoreactivities in Developing Chick Retina
- 주제(키워드) Chick embryo , Doublecortin , Retina , Stem cells
- 발행기관 한국현미경학회
- 발행년도 2012
- 총서유형 Journal
- UCI G704-000178.2012.42.3.005
- KCI ID ART001701360
- 본문언어 영어
초록/요약
Doublecortin (DCX) is a microtuble-associated protein that is required for the migration of immature neuroblasts within the chick and mammalian brain. Although it is generally thought that DCX is expressed only in the neuroblasts, some mature neurons maintain DCX expression; for example, horizontal cells in adult rat retina. In this study, we demonstrate that retinal neural progenitors in the early embryonic stage of the chick also expressed DCX, as do developing ganglion cells and horizontal cells in later stages of development. These findings raise the possibility of a role for DCX in retinal neural progenitors, before they become specialized into neuroblasts in the chick.
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