말기 신질환 환자들에서 발생한 말초신경병증 : Peripheral Neuropathy in Patients with End-Stage Renal Disease
Peripheral Neuropathy in Patients with End-Stage Renal Disease
- 주제(키워드) Peripheral neuropathy , End stage renal disease , Hemodialysis , Peritoneal dialysis , Diabetes mellitus
- 발행기관 대한근전도전기진단의학회
- 발행년도 2009
- 총서유형 Journal
- UCI G704-SER000010595.2009.11.2.020
- KCI ID ART001450284
- 본문언어 한국어
초록/요약
Objective: To investigate and analyze prevalence and characteristics of peripheral neuropathy in patients with end-stage renal disease (ESRD) according to the cause of ESRD. Methods: Cross sectional study was conducted in 112 patients who had undergone hemodialysis (n= 64) or peritoneal dialysis (n= 48). The medical records were reviewed. Standard motor and sensory nerve conduction studies, F waves, and H reflexes were performed. Peripheral neuropathy (PN) was diagnosed and classified into 4 grades. Results: PN was diagnosed in 58 patients (51.8%): 34 in hemodialysis (HD) group and 24 in peritoneal dialysis (PD) group. Forty two out of 47 patient with diabetes mellitus developed PN whereas 16 out of 65 did in non-diabetic patients (p<0.01). The severity of PN was as follows: Grade I, 12; Grade II, 11; Grade III, 26; Grade IV, 9. The duration of ESRD according to the severity of PN was not significant (p=0.056) in all the patients, but showed moderate correlation in non-diabetic patients (r=0.287, p<0.05). Conclusion: The diabetic patients may develop severe degree of PN compared to those with other etiology of ESRD because the peripheral nerve could be affected from both diabetes mellitus and uremia.
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