비스테로이드소염제 관련 소화성궤양의 예방과 치료 가이드라인 : Guidelines of Prevention and Treatment for NSAID-related Peptic Ulcers
Guidelines of Prevention and Treatment for NSAID-related Peptic Ulcers
- 주제(키워드) Non-steroidal anti-inflammatory drug , Peptic ulcer , Prevention , Guideline , Non-steroidal anti-inflammatory drug , Peptic ulcer , Prevention , Guideline
- 발행기관 대한소화기학회
- 발행년도 2009
- 총서유형 Journal
- UCI G704-000307.2009.54.5.005
- KCI ID ART001392299
- 본문언어 한국어
초록/요약
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications in Korea. Gastrointestinal toxicity, including peptic ulcer, is a common adverse effect of NSAIDs. Risk factors for NSAID-related peptic ulcer include a previous history of peptic ulcer, advanced age, high dose, concomitant use of corticosteroids, anticoagulants, other NSAIDs including low-dose aspirin. Preventive measure(s), such as COX-2 inhibitor, proton pump inhibitor or misoprostrol, should be done for patients requiring NSAID therapy who have high-risk factor(s) for peptic ulcer. Low dose aspirin also increases the risk of peptic ulcer, so preventive measure(s) should be done for high-risk patients. The eradication of Helicobacter pylori is recommended for high-risk NSAID-users. Treatment strategies for peptic ulcers in NSAID users are mostly the same for peptic ulcers in NSAID non-users.
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