생약초 청국장이 흰쥐의 혈액성분 및 뇨에 미치는 영향 : Effects of Herbal-cheonggukjang on Serum Composition and Urine in Rats
Effects of Herbal-cheonggukjang on Serum Composition and Urine in Rats
- 주제(키워드) Cheonggukjang , safety , herbal medicine , Cheonggukjang , safety , herbal medicine
- 발행기관 대한본초학회
- 발행년도 2008
- 총서유형 Journal
- UCI G704-000845.2008.23.2.018
- KCI ID ART001251212
- 본문언어 한국어
초록/요약
Ojectives : Cheonggukjang(natto) is known to have anti-hyperlipidemic action in our previous study. This study was designed to investigate the safety of Prototype-cheonggukjang (PC, Herbal-natto).Methods : We investigated the effects of PC on changes in body weights, food uptake, water uptake, levels of AST/ALT, levels of BUN/creatinine and electrolytes in serum from normal mice. PC is made by cheonggukjang added Codonopsis Lanceolata, Houttuynia cordata and Lentinus edodes in indicated concetrations.Results : In this experiment, PC group showed equal levels of body weights, urine volume compared to non-treated control group. Oral administration of PC did not affect food and water uptake too. Levels of AST/ALT, which are markers of liver function, were not changed by administration of PC. In addition, levels of BUN/creatinine, which are markers of renal function, were not affected by PC too. Finally electrolytes in serum were not affected by PC.Conclusions : These results imply that oral administration of PC is safe in the framework of liver and renal function, and electrolytes in serum.
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