小靑龍湯이 喘息이 유발된 생쥐의 면역 글로불린 분비에 미치는 영향 : Effects of Socheongryong-Tang on Immunoglobulin Production in Asthmatic Mice
Effects of Socheongryong-Tang on Immunoglobulin Production in Asthmatic Mice
- 주제(키워드) Socheongryong-Tang , IgE , IgG1 , Herbal medicine , Asthma , Socheongryong-Tang , IgE , IgG1 , Herbal medicine , Asthma
- 발행기관 대한본초학회
- 발행년도 2008
- 총서유형 Journal
- UCI G704-000845.2008.23.1.011
- KCI ID ART001239925
- 본문언어 한국어
초록/요약
Objectives : Socheongryong-Tang(小靑龍湯, SCRT), a herbal remedy, has been widely used to treat respiratory disease such as cough and asthma in Oriental countries. Recent years SCRT was known as anti-allergic agent. However, its therapeutic mechanisms including immunoglobuline such as IgE, IgG1, IgG2a productions are unclear. Methods : We investigated the effects of SCRT on levels of antigen specific total antibody, IgE, IgG1, IgG2a using ELISA method in serum from allergen-induced asthma mice. Results : SCRT decreased level of antigen specific IgE significantly. And SCRT treated mice showed downward tendency of IgG1, a Th1 relative antibody, level. But, SCRT did not affect levels of antigen specific total antibody and IgG2a, a Th1 relative antibody. Conclusions : we demonstrated the strong possibility of SCRT as a complementary or alternative drug to western drug also demonstrated that regulation of Th1/Th2 imbalance may be one of mechanism contributed to treatment for respiratory disease by SCRT.
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