Effective Methods to Improve the Biocompatibility of Poly(dimethylsiloxane)
Effective Methods to Improve the Biocompatibility of Poly(dimethylsiloxane)
- 주제(키워드) Biocompatibility , PDMS , Microfluidic chip , Fibroblast
- 발행기관 한국바이오칩학회
- 발행년도 2008
- 총서유형 Journal
- UCI G704-SER000001574.2008.2.1.008
- KCI ID ART001364228
- 본문언어 영어
초록/요약
Poly (dimethylsiloxane) (PDMS) has become one of the popular materials in the field of bio-related microfluidic systems, and has been used for various biological assays. While the material is known to be biocompatible in general, it also has been reported that the attachment and survival rate of cells are limited on a PDMS substrate. In this paper, a simple and relevant method to improve heiocompatibilityof PDMS is proposed; the effects of various treatments using ethanol, water, and boiling-water were evaluated. The results show that the boiling-water treatment is the most appropriate, time saving, and simple method to improve the biocompatibility of PDMS.
more