괴저성 농피증의 양상으로 나타난 Wegener 육아종증 : Wegener's Granulomatosis Presenting as Pyoderma Gangrenosum
Wegener's Granulomatosis Presenting as Pyoderma Gangrenosum
- 주제(키워드) ANCA , Pyoderma gangrenosum , Wegener's granulomatosis
- 발행기관 대한피부과학회
- 발행년도 2008
- 총서유형 Journal
- UCI G704-000562.2008.46.1.004
- KCI ID ART001222166
- 본문언어 한국어
초록/요약
Wegener's granulomatosis (WG) is a systemic disease of unknown origin characterized by necrotizing granulomatous inflammation and vasculitis. Dermatological symptoms occur in up to 50% of cases, mostly in the form of cutaneous vasculitis or pyoderma gangrenosum. A 51-year-old female presented with multiple ulcerative patches and erythematous nodules on both legs. Histopathological findings showed extensive ill-defined granulomatous lesions and necrotizing vasculitis. Lung biopsy findings were consistent with WG. Nasopharyngeal and gastrointestinal involvement developed later. Skin lesions are improving with systemic corticosteroid and cyclophosphamide. We herein report a case of WG presenting as pyoderma gangrenosum-like cutaneous manifestation with other systemic involvements.
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