기관지내 종괴로 발현된 일차성 폐 형질 세포종 1예 : A Case of Primary Pulmonary Plasmacytoma Presenting as Endobronchial Mass
A Case of Primary Pulmonary Plasmacytoma Presenting as Endobronchial Mass
- 발행기관 대한결핵및호흡기학회
- 발행년도 2004
- 총서유형 Journal
- UCI G704-000421.2004.56.6.006
- KCI ID ART001117220
초록/요약
Extramedullary plasmacytoma(EMP) comprises 5% of all plasma cell neoplasms and commonly occurs in the upper airway or digestive tract. However, it rarely develops in the lungs. We present a case of primary pulmonary plasmacyotma in a 45 year old man, who presented as an endobronchial mass with a pleural effusion, but without evidence of multiple myeloma. The treatment options for EMP include surgery, surgery and radiotherapy, surgery and chemotherapy or chemotherapy alone. Surgery and radiation therapy appeared to be equally effective forms of treatment. The local recurrence rate was reported to be 30%, with 48% progressing to multiple myeloma, and median survival was reported to be 63-101 months. Our patient was initially treated with melphalan and prednisolone. However the disease progressed, and radiotherapy was combined with chemotherapy. In addition, the chemotherapy regimen was also changed to thalidomide and dexamethasone. The patient did not respond to this treatment regimen and finally died.(Tuberculosis and Respiratory Diseases 2004, 56:664-669)
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