The Short Breath-Hold Technique as the First Step to Overcoming a Degraded Hepatic Arterial Phase in Liver MR imaging: A Prospective Randomized Control Study
간 MRI에서 동맥기영상의 손상을 극복하기 위한 첫걸음으로서의 짧은 숨참기 기법: 전향적 무작위 대조군 연구
- 주제(키워드) gadoxetic acid , liver , magnetic resonance imaging , controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) , breath-hold , arterial phase , dyspnea
- 발행기관 고려대학교 대학원
- 지도교수 설혜영
- 발행년도 2016
- 학위수여년월 2016. 8
- 학위구분 박사
- 학과 대학원 의학과
- 세부전공 영상의학과학 전공
- 원문페이지 53 p
- 실제URI http://www.dcollection.net/handler/korea/000000069030
- 본문언어 영어
- 제출원본 000045884645
초록/요약
Purpose : To assess whether a short breath-hold technique can improve hepatic arterial phase image quality in gadoxetic acid-enhanced magnetic resonance imaging (MRI) compared to a conventional long breath-hold technique. Materials and Methods : Institutional review board approval and patient informed consent were obtained for this prospective randomized control study. One hundred nineteen patients who were randomly allocated into two groups underwent an 18-second long breath-hold MR technique (group A) or a 13-second short breath-hold MR technique (group B) during gadoxetic acid-enhanced MRI. Respiratory-related graphs were acquired during the acquisition of the precontrast and hepatic arterial phases. For quantitative analysis, the breath-hold degree was graded on a four-point scale based on the standard deviation (SD) value of the respiratory waveforms, with the highest grade indicating the worst breath-hold. When the SD value of the hepatic arterial phase was 200 greater than that during the precontrast phase without degraded image quality in the portal and transitional phases, it was defined as gadoxetic acid-related dyspnea. For qualitative analysis, overall image quality, motion artifacts, liver margin sharpness, and hepatic artery clarity of the precontrast and hepatic arterial phase images were evaluated using a five-point scale with the highest mean score indicating the poorest image quality. Comparisons between the two groups were made with the Student t or Fisher exact test, as appropriate. Result : Based on respiratory waveform analysis, the incidence of breath-holding difficulty (breath-hold grades 3 and 4) was 33.87% (21/62) for group A, 21.05% (12/57) for group B during the precontrast phase and 43.55% (27/62) for group A, 36.84% (21/57) for group B during the hepatic arterial phase. The SD value during the precontrast phase and the SD value difference between the precontrast and hepatic arterial phases were both significantly higher in group A than in group B (p = 0.047 and p = 0.023, respectively). The incidence of gadoxetic acid-related dyspnea during the hepatic arterial phase was 19.35% (12/62) for group A and 7.02% (4/57) for group B. Based on image analysis, the mean image quality scores of group A were significantly higher than group B (all p < 0.001). Degraded hepatic arterial phase (overall image quality ≥ 4) was observed in 9.68% (6/62) of group A and 3.51% (2/57) of group B. Conclusion : The short breath-hold MR technique showed better hepatic arterial phase image quality with less degraded hepatic arterial phase and a lower incidence of breath-hold difficulty and gadoxetic acid-related dyspnea than the conventional long breath-hold MR technique.
more목차
I. Introduction ----------------------------- 1
II. Materials and Methods ------------------ 3
III. Results -------------------------------- 13
IV. Discussion ---------------------------- 19
References ------------------------------ 27
