CONTINUOUS PARTICLE SEPARATION BASED ON DIELETROPHORESIS IN AN ASYMMETRICALY U-SHAPED MICROCHANNEL
- 주제(키워드) DIELETROPHORESIS , SEPARATION
- 발행기관 고려대학교 대학원
- 지도교수 천홍구
- 발행년도 2013
- 학위수여년월 2013. 8
- 학위구분 석사
- 학과 일반대학원 기계공학과
- 세부전공 열및유체공학전공
- 원문페이지 75 p
- 실제URI http://www.dcollection.net/handler/korea/000000046658
- 본문언어 영어
- 제출원본 000045764655
초록/요약
This study is an invstigation to research on particle separation by incorporating Dielectrophoresis (DEP) theories. study started with related literature review regarding DEP force and separating mechanism. It was confirmed that DEP, in biotechnology, serves as an appropriate mechanism in manipulating and separating cells for no risk to cause damage to the sample. Here, a method of particle-size separation mechanism in an evaporating droplet is demonstrated. The method utilizes the dc-dielectrophoretic (dc-DEP) force created in a microchannel under an applied dc electric field. Micropatterned electrodes of Au were fabricated on the silicon dioxide layer and were used to generate dielectrophoresis. This method does not require a complicated electrode array which is commonly used in the conventional ac-DEP system. Polystyrene particles were used as separating objects. Micro-particles mixed in water were separated using the combination of an electrical force due to dielectrophoresis and a mechanical one generated in microchannel. The experiments showed that the separation of the micron-sized particles can be controlled by the DEP force under electric-field potentials of 3-5V. Based on this work, the microparticles can be separated and controlled
more목차
ABSTRACT I
TABLE OF CONTENTS II
LIST OF FIGURES IV
NOMENCLATURE VII
CHAPTER1 1
1 INTRODUCTION 1
1.1 Particle Separation Methods and Theoretical Background 3
1.1.1 Acoustic Separation 3
1.1.2 Magnetic Separation 4
1.1.3 Mechanical Separation 5
1.1.4 Electrochemical Separation 6
1.1.5 Electrical Separation 7
1.2 Electrical Separation Methods in the Literature 9
1.3 Research Objectives and Thesis Organization 13
CHAPTER 2 16
2 THEORY OF DIELECTROPHORESIS 16
2.1 Direct Dielectrophoresis (DEP) 16
2.2 Travelling Wave Dielectrophoresis (TWD) 24
2.3 Electrorotation 25
2.4 Strategies for Applications of Dielectrophoresis 27
2.4.1 Castellated Electrodes 27
2.4.2 Ratchet Electrodes 28
2.4.3 Concentric Electrodes 29
2.4.4 Quadruple Electrodes 30
2.4.5 Parallel Electrodes 31
2.4.6 Spiral Electrodes 32
2.4.7 Insulating Obstacles and Deformations on the Channel 32
2.5 Techniques of Dielectrophoresis 33
CHAPTER 3 35
3 Design of dielectrophoretic separation of micro particles 35
3.1 Physical Structure of the Dielectrophoretic Particle Separator 35
3.2 Theoretical Explanation of the Device 38
3.3 Theory 40
3.4 Design Parameters and Trade-Off 41
3.5 Simulations Based on FEM 44
3.6 . FEM SIMULATIONS OF ALL SETS OF DEVICES 48
CHAPTER 4 50
4 FABRICATION AND EXPERIMENTATION OF THE DIELECTROPHORETIC SEPARATOR 50
4.1 Experimental Method (DC Dielectrophoresis) 53
CHAPTER 5 56
5 CONCLUSIONS AND FUTURE RESEARCH OBJECTIVES 56
REFERENCES 60
