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Obstructive sleep apnea is related to atrial fibrillation recurrence after catheter ablation in patients with longstanding persistent atrial fibrillation

  • 이대인 (대학원 의학과 내과학전공)

초록/요약

BACKGROUND Obstructive sleep apnea (OSA) is well known as a risk factor for atrial fibrillation (AF). However, it remains unclear whether OSA can be of predictive value forAF recurrence after extensive CFAE-guided ablation of longstanding persistent AF (LPAF). METHODS One hundred and sevenconsecutive LPAF patients who underwent complex fractionated atrial electrograms(CFAEs)guided ablation in addition to pulmonary vein isolation (PVI) were included. Based on the Berlin Questionnaire (BQ), we classified study population into low and high risk group for OSA. RESULTS During23.0？b7.7months, the recurrence rate of AFwas higher in patients with high risk for OSAthan those with low risk (79.4% vs 38.4%, p=0.0001). In the Kaplan-Meier estimates, AF recurrence after 12 months in patients with low risk waslower than those with high risk. (15.5% vs35.3%, log-rank p = 0.0001). Using the multivariate Cox analysis, risk for OSA, was independent predictor of AF recurrence, after adjusting multiple variables including age, sex, AF duration, body mass index (BMI), left atrial volume (hazards ratio of 2.18, 95% CI 1.15 to4.11, p = 0.017). CONCLUSIONS The high risk for OSA assessed by BQwas independently related to the recurrence of AF after biatrial CFAE ablation in patients with LPAF.

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목차

1. Introduction -------------------------------------------- 1page
2. Methods and Materials ------------------------------- 2-5 page
3. Results --------------------------------------------------- 6 page
4. Discussion ----------------------------------------------- 7-9 page
5. Limitation ----------------------------------------------- 10page
6. Conclusion ---------------------------------------------- 11 page
7. Reference ------------------------------------------------ 15-17 page

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