Gray and Power Doppler Study of Biopsy Proven Kikuchi Disease
- 주제(키워드) Kikuchi disease , Cervical lymphadenopathy , Sonography , Gray scale , Power Doppler Study
- 발행기관 고려대학교 대학원
- 지도교수 설혜영
- 발행년도 2011
- 학위수여년월 2011. 8
- 학위구분 석사
- 학과 일반대학원 의학과
- 세부전공 영상의학과학전공
- 원문페이지 31 p
- 실제URI http://www.dcollection.net/handler/korea/000000026534
- 본문언어 영어
- 제출원본 000045667895
초록/요약
Purpose : Kikuchi disease is a benign, self-limiting cause of cervical lymphadenopathy. Kikuchi disease can show ultrasound (US) features similar to those of other common causes of lymphadenopathy. The purpose of this study is to characterize the US features of Kikuchi disease that can contribute in differentiating between Kikuchi disease and other diseases causing cervical lymphadenopathy. Materials and Methods : US findings of 175 patients with biopsy proven Kikuchi disease were retrospectively reviewed. The mean age of the patients was 27.3 years, with a range of 8-56 years and the female to male ratio was 3.5:1. All patients had undergone US-guided core biopsy. Pathologic findings were classified into proliferative (n=57), necrotizing (n=109), and xanthomatous (n=9) types. On gray scale, lymph nodes (LN) were assessed by their size, shape (shortest/longest axis ratio), location, echogenicity, conglomeration, gross necrosis, calcification, echogenic hilum, and increased perinodal echogenicity. The vascular pattern of the LNs was assessed on power Doppler sonography. Result : The mean maximum diameter of the LNs was 1.6 cm, demonstrating a wide range of 0.8-3.5 cm. 44% (77/175) of the LNs were oval (S/L=0.5-0.7), 48% (84/175) were elongated (S/L<0.5), 5.1% (9/175) were round (S/L>0.7) and 2.9% (5/175) were conglomerated. Most of the LNs were located in levels II and V. Seventeen LNs showed gross necrosis and none demonstrated calcification. One hundred fifty two (86.9%) LNs had an echogenic hilum and one hundred thirty three (76%) showed increased perinodal echogenicity. Increased perinodal echogenicity was seen in 93.5% (102/109) of the necrotizing type, 43.8% (25/57) of the proliferative type, and 66.7% (6/9) of the xanthomatous type; the difference between the necrotizing and proliferative types was statistically significant (P=.001). Normal (n=161), displaced (n=13), and absent (n=1) hilar vascularities were seen on power Doppler study sonography. Conclusion : The US findings demonstrating elongated or oval hypoechoic lymph nodes with increased perinodal echogenicity, an echogenic hilum, and normal hilar flow are helpful findings in the differentiation of Kikuchi disease with other causes of cervical lymphadenopathy.
more목차
Abstract i
Introduction 1
Materials and Methods 3
Results 6
Discussion 8
References 13
Tables 15
Figures and Legends 16
